CARGLUMIC ACID

Overview

CARGLUMIC ACID is a Schedule H drug.
Carglumic acid is a man-made form of an enzyme that occurs naturally in the liver. This enzyme is necessary for processing excess nitrogen produced when the body metabolizes proteins. Without this enzyme, nitrogen builds up in the form of ammonia and is not removed from the body. Ammonia is very toxic when it circulates in blood and tissues and can cause permanent brain damage, coma, or death.Carglumic acid is used to treat hyperammonemia, a urea cycle disorder caused by lack of a certain liver enzyme. Carglumic acid is usually given with other medications to treat this lifelong disorder.Some patients have a deficiency in an enzyme called N-acetylglutamate synthase (NAGS). NAGS is involved in activating a protein that is responsible for breaking down ammonia in the blood. In patients with a deficiency in NAGS, ammonia levels in the blood can become too high.Carglumic acid is approved for the treatment of acute or chronic hyperammonemia in patients with NAGS deficiency.

Usage

CARGLUMIC ACID is generally used to treat: Hyperammonemia
CARGLUMIC ACID can address symptoms like: Restless Or Irritability, Vomit, Hyperventilating (rapid/deep Breathing)

Frequently Asked Questions

Q: Is it safe on my liver?
A: Check with your Doctor first

Q: Is it safe on my kidney?
A: Check with your Doctor first

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Ask your doctor

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

Q: Is it safe to take for someone breastfeeding?
A: Not Safe

How Do I Take It?

CARGLUMIC ACID is generally taken Before Food.
Route of Administration: Oral

Precautions

  • Carglumic acid is only part of a complete program of treatment that may also include a special diet and other medications.
  • Follow all instructions of your doctor or dietitian. Learn about the foods to eat or avoid to help control your condition.
  • Follow all directions on your prescription label and read all medication guides or instruction sheets.
  • Your doctor may occasionally change your dose. Use the medicine exactly as directed.
  • Carglumic acid is usually taken 2 to 4 times each day, just before each meal or feeding. Follow your doctor’s instructions.
  • Do not crush or swallow the dispersible tablet whole. Place it into a glass of water and allow the tablet to disperse (it will not dissolve completely). Drink this mixture right away. Add a little more water to the glass, swirl gently and drink right away.
  • Your blood will need to be tested often. A buildup of ammonia in the blood can quickly cause brain injury or death. Even if you have no symptoms, tests can help your doctor determine if this medicine is effective.
  • Every person with a urea cycle disorder should remain under the care of a doctor.Take your dose as soon as you can, but only if you are getting ready to eat a meal. If you skip a meal, skip the missed dose and wait until your next meal. Do not take two doses at one time.
  • Avoid eating foods that are high in protein when you first start taking carglumic acid.

Symptoms of Overdosage

CARGLUMIC ACID over-dosage can result in: Fever, Rapid Heart Rate (pulse), Cough, Restless Or Irritability

Common Side-Effects

CARGLUMIC ACID : Diarrhoea, Stomach Pain, Vomit, Abdomen Pain, Head Headache, Fever, Throat Soreness

Serious Side-Effects

CARGLUMIC ACID : Muscle Pain, Joint Pain, Skin Rash, Stomach Pain, Chills, Cough, Weight Loss (intentional), Body Excessive Sweating, Loss Of Appetite, Lower Back Pain, Body Discomfort, Runny Nose, Difficulty Urinating, Pale Skin, Throat Soreness, Difficulty Sleeping, Weakness (generalized)

Technical Classification

CARGLUMIC ACID is categorized as: MISCELLANEOUS UNCATEGORIZED AGENTS / MISCELLANEOUS AGENTS

Storage Conditions

Refrigeration (Between 2 To 8 C)

Available Alternatives

What are the other drugs with similar Ingredients?

CARGLUMIC ACIDCARGLUMIC ACID