KOFF GO TAB

Overview

KOFF GO TAB is a Schedule H drug.

KOFF GO TAB is composed of: PARACETAMOL (450.0 MG), GUAIFENESIN (50.0 MG), EPHEDRINE (5.0 MG), BROMHEXINE (4.0 MG), CHLORPHENIRAMINE (2.0 MG)

Paracetamol is a pain reliever and a fever reducer. The exact mechanism of action of is not known. Paracetamol is used to treat many conditions such as a headache, muscle aches, arthritis, backache, toothaches, colds, and fevers. It relieves pain in mild arthritis but has no effect on the underlying inflammation and swelling of the joint.

Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.Guaifenesin is used to reduce chest congestion caused by the common cold, infections, or allergies.It promotes lower respiratory tract drainage by thinning the mucus in the air passages to make it easier to cough up the mucus and clear the airways. 


Ephedrine works on the blood vessels and increases the blood flow to heart and lungs, thereby improving the disease condition. Ephedrine is used in the treatment of hypotension following spinal anaesthesia. Ephedrine is used for temporary relief of shortness of breath, chest tightness, and wheezing due to bronchial asthma. Ephedrine may also be used for other conditions as determined by your doctor. Ephedrine is a decongestant and bronchodilator. It works by reducing swelling and constricting blood vessels in the nasal passages and widening the lung airways, allowing you to breathe more easily.

Chlorpheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose Chlorpheniramine is used to treat runny nose, sneezing, itching, and watery eyes caused by allergies, thecommon cold, or the flu..

Usage

PARACETAMOL is generally used to treat: Arthritis
PARACETAMOL can address symptoms like: Head Headache, Back Pain, Cold, Fever

GUAIFENESIN is generally used to treat: Bronchitis, Laryngitis, Pharyngitis, Rhinitis, Sinusitis, Whooping Cough
GUAIFENESIN can address symptoms like: Shortness Of Breath, Difficulty Breathing, Wheezing, Cough, Chest Pain, Chest Discomfort, Fever, Head Headache, Fatigue (tiredness), Rapid Heart Rate (pulse)

EPHEDRINE is generally used to treat: Hypotension, Bronchial Asthma
EPHEDRINE can address symptoms like: Shortness Of Breath, Tightness, Wheezing


CHLORPHENIRAMINE is generally used to treat: Common Cold
CHLORPHENIRAMINE can address symptoms like: Sneezing, Body Itching, Eyes Watery Eyes, Runny Nose

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 1month

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

Q: Is it safe to take for someone breastfeeding?
A: Not Safe

Precautions for KOFF GO TAB and its Constituents


Caution should be exercised in patients with history of asthma, bleeding problems, growths in the nose, heart, kidney or liver disease, liver inflammation, high blood pressure, chickenpox, anxiety, trouble in sleeping, ulcers, stomach problems, stroke, Kawasaki syndrome, any allergy, who are taking other medications, during pregnancy and breastfeeding. Avoid alcohol consumption. It should not be used in children with infections such as flu, chickenpox or viral infections. Avoid large amount of caffeinated beverages while taking this medication. It may reduce platelet counts; avoid injury or bruising.
  • You should not use guaifenesin if you are allergic to guaifenesin.
  • Use guaifenesin exactly as directed on the label, or as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended.
  • Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication.
  • Take guaifenesin with food if it upsets your stomach.Measure the liquid form of guaifenesin with a special dose-measuring spoon or cup, not a regular table spoon.
  • Do not crush, chew, break, or open a controlled-release, delayed-release, or extended-release tablet or capsule. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time.
  • Do not take extra medicine to make up the missed dose.
  • This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
  • The liquid forms and powder packets of this medication may contain aspartame. If you have phenylketonuria  or any other condition that requires you to restrict your intake of aspartame (or phenylalanine), consult your doctor or pharmacist about using this product safely.
  • Use within 4 weeks of opening the bottle; discard after 4 weeks of opening even if not used

Caution should be exercised in patients with history of heart disease, overactive thyroid, diabetes, high blood pressure, increased eye pressure, kidney impairment, prostate enlargement, elderly, during pregnancy. It may cause dizziness, drowsiness, do not drive a car or operate machinery while taking this medication. Avoid excess dosage.

  • Avoid excess dosage.
  • Avoid long-term use of this medication.
  • Caution should be exercised in patients with history of asthma, lung disease, heart problems, high blood pressure, sugar, blood vessel problems, stroke, increased eye pressure, intestinal blockage, ulcer, urinary obstruction, enlarged prostate, seizures, overactive thyroid, any allergy, who are taking other medications, elderly, children, during pregnancy and breast feeding.

Symptoms of Overdosage

PARACETAMOL over-dosage can result in: Loss Of Appetite, Nausea, Vomit, Abdomen Pain, Weakness (generalized), Upper Abdomen Pain, Dark Colored (brown) Urine, Eyes Yellow Eyes
EPHEDRINE over-dosage can result in: Difficulty Breathing

Common Side-Effects

GUAIFENESIN : Diarrhoea, Skin Rash, Hives, Dizziness, Head Headache, Nausea, Vomit, Abdomen Upset Stomach
EPHEDRINE : Hypertension, Insomnia, Difficulty Sleeping
CHLORPHENIRAMINE : Fever, Wheezing, Tightness, Difficulty Breathing, Hoarse Voice, Face Swelling, Drowsiness, Fatigue (tiredness), Nervousness, Frequent Urination, Arms Joint Pain, Eyes Double Vision (with One Eye Covered)

Serious Side-Effects

GUAIFENESIN : Breathlessness, Difficulty Breathing

Rare Side-Effects

PARACETAMOL : Skin Rash, Dizziness, Difficulty Breathing, Face Swelling, Body Itching

Disease Interactions

CHLORPHENIRAMINE can interfere with: Urinary Retention, Glaucoma, Asthma, COPD, Hypotension, Acute Liver Failure

Technical Classification

PARACETAMOL is categorized as: MISCELLANEOUS ANALGESICS / ANALGESICS / CENTRAL NERVOUS SYSTEM AGENTS
GUAIFENESIN is categorized as: EXPECTORANTS / RESPIRATORY AGENTS
EPHEDRINE is categorized as:
  • DECONGESTANTS / RESPIRATORY AGENTS
  • VASOPRESSORS / CARDIOVASCULAR AGENTS

CHLORPHENIRAMINE is categorized as: NASAL ANTIHISTAMINES AND DECONGESTANTS / NASAL PREPARATIONS / TOPICAL AGENTS

Available Alternatives for KOFF GO TAB

What are the commonly available Substitutes?

KOFF GO TABINR 22 for 10 TABLETSPARACETAMOL 450.0 MG, GUAIFENESIN 50.0 MG, EPHEDRINE 5.0 MG, BROMHEXINE 4.0 MG, CHLORPHENIRAMINE 2.0 MG

What are the other drugs with similar Ingredients?

FREKOF TABINR 19.5 for 10 TABLETSPARACETAMOL 500.0 MG, GUAIFENESIN 50.0 MG, EPHEDRINE 5.0 MG, BROMHEXINE 4.0 MG, CHLORPHENIRAMINE 2.0 MG