VIROTRENZ 200MG/300MG/600MG TAB

Contents

1 Overview
2 Usage
3 Frequently Asked Questions
4 How Do I Take It?
5 Precautions
6 Symptoms of Overdosage
7 Common Side-Effects
8 Rare Side-Effects
9 Disease Interactions
10 Technical Classification
11 Available Alternatives
- 11.1 What are the commonly available Substitutes?
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Overview

VIROTRENZ 200MG/300MG/600MG TAB is a Schedule H drug.

VIROTRENZ 200MG/300MG/600MG TAB is composed of: EFAVIRENZ (600.0 MG), TENOFOVIR (300.0 MG), EMTRICITABINE (200.0 MG)

Efavirenz is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body. Efavirenz is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). Efavirenz is for adults and children who are at least 3 months old and weigh at least 8 pounds. Efavirenz is not a cure for HIV or AIDS.

Tenofovir is used to treat chronic hepatitis B infection, a viral infection of the liver. It works by stopping or slowing the growth of the virus. Chronic hepatitis infection can lead to serious liver damage (cirrhosis) and liver cancer. This medication is a class of antiretroviral agent, prescribed for HIV infection in combination with other medicines, and chronic hepatitis B in adults. Tenofovir is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). Tenofovir is not a cure for HIV or AIDS.
Emtricitabine is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body. Emtricitabine is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). Emtricitabine is not a cure for HIV or AIDS.

Usage

EFAVIRENZ is generally used to treat: AIDS

TENOFOVIR is generally used to treat: Hepatitis B, AIDS, Human Immunodeficiency Virus

EMTRICITABINE is generally used to treat: Human Immunodeficiency Virus, AIDS

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 3yrs

Q: Can it be taken during pregnancy?
A: Studies indicate Risk – Doctor advice is must

Q: Is it safe to take for someone breastfeeding?
A: Check with your Doctor first

How Do I Take It?

VIROTRENZ 200MG/300MG/600MG TAB is generally taken Before Food.

Precautions

Efavirenz must be given in combination with other antiviral medications and it should not be used alone. Your disease may become resistant to efavirenz if you do not take it in combination with other HIV medicines your doctor has prescribed. Take efavirenz on an empty stomach at bedtime. To make swallowing easier, you may open an efavirenz capsule and sprinkle the medicine into a spoonful of applesauce, yogurt, or grape jelly. You may also mix the medicine with infant formula if you are giving the medicine to a baby. Swallow the mixture right away. Do not save it for later use. After taking efavirenz using the sprinkle method, do not eat for the next 2 hours. Efavirenz mixed with infant formula should be given to the baby right away. But do not feed the baby any more formula for at least 2 hours afterward. Efavirenz comes with instructions for mixing the capsule contents with soft food or infant formula. Follow these directions carefully. Do not crush, chew, or break an efavirenz tablet. Swallow it whole with liquid. Drinking alcohol can increase certain side effects of efavirenz. Taking this medication will not prevent you from passing HIV to other people. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.

Some forms of tenofovir should be taken with food. Carefully follow all instructions on your medicine label.
Avoid drinking alcohol. It may increase your risk of liver damage.
Caution should be exercised in patients with history of liver problems, including HBV infection, bone problems or kidney problems, any allergy, during pregnancy and breastfeeding.
It may cause dizziness, do not drive a car or operate machinery while taking this medication.
It does not stop the spread of HIV or HBV to others through blood or sexual contact.
Before taking tenofovir alafenamide, tell your doctor or pharmacist if you are allergic to it or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Caution should be exercised in patients with history of hepatitis B, kidney disease, lactic acidosis, liver disease, obesity, any allergy, who are taking other medications, children, during pregnancy and breastfeeding. It may cause dizziness, do not drive a car or operate machinery while taking this medication. It does not stop the spread of HIV to others; avoid sexual contacts, sharing of needles, or injection supplies. Monitor liver and kidney function regularly while taking this medication.

Symptoms of Overdosage

EFAVIRENZ over-dosage can result in: Difficulty Breathing

Common Side-Effects

EFAVIRENZ : Depression, Skin Rash, Body Itching, Blood Or Red Colored Urine, Pain With Urination, Lower Back Pain
TENOFOVIR : Chest Pain, Cough, Fever, Chills, Difficulty Breathing
EMTRICITABINE : Goiter, Guillan-Barre Syndrome, Paralysis, Head Headache, Difficulty Sleeping, Black Colored Skin, Weight Loss (unintentional), Difficulty Breathing, Slurred Speech, Cough, Nervousness, Fever, Chills, Restless Or Irritability

Rare Side-Effects

EFAVIRENZ : Hives, Abdomen Pain, Confusion, Seizures (uncontrollable Jerking Of Limbs), Cough, Dark Colored (brown) Urine, Fainting, Fever, Chills, Head Headache, Loss Of Appetite, Nausea, Vomit
TENOFOVIR : Abdomen Pain, Decreased Appetite, Loose Motion, Shortness Of Breath, Slow Or Irregular Breathing, Fatigue (tiredness), Weakness (generalized)
EMTRICITABINE : Lactic Acidosis, Skin Rash, Mood Swings, Nausea, Vomit, Abdomen Pain, Eyes Yellow Eyes, Dark Colored (brown) Urine, Drowsiness, Body Itching, Face Swelling

Disease Interactions

EMTRICITABINE can interfere with: Acute Renal Failure

Technical Classification

EFAVIRENZ is categorized as: NNRTIS / ANTIVIRAL AGENTS / ANTI-INFECTIVES
TENOFOVIR is categorized as: NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS (NRTIS) / ANTIVIRAL AGENTS / ANTI-INFECTIVES
EMTRICITABINE is categorized as: NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS (NRTIS) / ANTIVIRAL AGENTS / ANTI-INFECTIVES

Available Alternatives

What are the commonly available Substitutes?

FORSTAVIR 200MG/300MG/600MG TAB	INR 2380.95 for 30 TABLETS	EFAVIRENZ 600.0 MG, TENOFOVIR 300.0 MG, EMTRICITABINE 200.0 MG
FORSTAVIR EM TAB	INR 1272.9 for 30 TABLETS	EMTRICITABINE 300.0 MG, TENOFOVIR 200.0 MG, EFAVIRENZ
TEEVIR 200MG/300MG/600MG TAB	INR 4000 for 30 TABLETS	EFAVIRENZ 600.0 MG, TENOFOVIR 300.0 MG, EMTRICITABINE 200.0 MG
TOFODAY 200MG/300MG/600MG TAB	INR 4330.67 for 30 TABLETS	EFAVIRENZ 600.0 MG, TENOFOVIR 300.0 MG, EMTRICITABINE 200.0 MG
TRUSTIVA 200MG/300MG/600MG TAB	INR 3800 for 30 TABLETS	EFAVIRENZ 600.0 MG, TENOFOVIR 300.0 MG, EMTRICITABINE 200.0 MG
VIRADAY 200MG/300MG/600MG TAB	INR 3900 for 30 TABLETS	EFAVIRENZ 600.0 MG, TENOFOVIR 300.0 MG, EMTRICITABINE 200.0 MG
VIROTRENZ 200MG/300MG/600MG TAB	INR 3714.36 for 30 TABLETS	EFAVIRENZ 600.0 MG, TENOFOVIR 300.0 MG, EMTRICITABINE 200.0 MG
VONAVIR 200MG/300MG/600MG TAB	INR 3900 for 30 TABLETS	EFAVIRENZ 600.0 MG, TENOFOVIR 300.0 MG, EMTRICITABINE 200.0 MG