Canakinumab is a monoclonal antibody that blocks certain proteins in the body that can affect inflammation and other immune responses. This medication is an interleukin-1 beta-blocker, prescribed for auto-inflammatory diseases known as cryopyrin-associated periodic syndrome (CAPS). It decreases interleukin-1 beta’s activity. Canakinumab is used to treat certain types of periodic fever syndromes, sometimes called auto-inflammatory syndromes. It is also approved to treat systemic juvenile idiopathic arthritis (SJIA) in children two years and older.


CANAKINUMAB is generally used to treat: Fever, Juvenile Rheumatoid Arthritis

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Check with your Doctor first

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 18month

Q: Can it be taken during pregnancy?
A: Considered as Generally Safe – not enough studies to prove risk

Q: Is it safe to take for someone breastfeeding?
A: Check with your Doctor first

How Do I Take It?

Route of Administration: IV (Intravenous)


  • Before using canakinumab, tell your doctor or pharmacist if you are allergic to it or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
  • This drug may make you dizzy. Alcohol can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages.
  • Before starting this drug, you should take a tuberculosis (TB) skin test to check for a type of tuberculosis that may not be causing any symptoms (latent TB). If you are diagnosed with TB, you must first be treated for it before you start canakinumab to prevent a serious TB infection.
  • Canakinumab can make you more likely to get infections or may worsen any current infections. Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu).
  • Do not have immunizations/vaccinations without the consent of your doctor. Avoid contact with people who have recently received live vaccines.
  • During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
  • It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

Common Side-Effects

CANAKINUMAB : Body Pain, Chills, Nasal Congestion, Cough, Loose Motion, Dry Mouth, Fever, Head Headache, Loss Of Appetite, Nausea, Shortness Of Breath, Sneezing, Runny Nose, Body Excessive Sweating, Chest Discomfort, Difficulty Sleeping, Difficulty Swallowing, Vomit

Rare Side-Effects

CANAKINUMAB : Weight Gain, Fainting

Disease Interactions

CANAKINUMAB can interfere with: Tuberculosis

Technical Classification


Storage Conditions

Refrigeration (Between 2 To 8 C)

Available Alternatives

What are the other drugs with similar Ingredients?