SAFINAMIDE is a Schedule H drug.
Safinamide is monoamine oxidase inhibitor type B (MAO-B). safinamide works by allowing a chemical called dopamine (DOE pa meen) to work for longer periods of time in the brain. Low levels of dopamine in the brain are associated with Parkinson’s disease. Safinamide is given with levodopa and carbidopa to treat "wearing-off" episodes (muscle stiffness, loss of muscle control) in people with Parkinson’s disease.


SAFINAMIDE is generally used to treat: Parkinson’s Disease
SAFINAMIDE can address symptoms like: Muscle Stiffness

Frequently Asked Questions

Q: Is it safe on my liver?
A: Check with your Doctor first

Q: Is it safe on my kidney?
A: Check with your Doctor first

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Ask your doctor

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

How Do I Take It?

Route of Administration: Oral


Patients should be informed that safinamide can increase blood pressure even at the recommended dose of safinamide. Patients on safinamide are at a risk of drowsiness, therefore patients should be advised not to drive or operate heavy machinery or work at heights while on the medication. Patients should be asked to report to the physician immediately if they experience a compulsive behavior such as the urge to gamble, spend more money, binge eating or sexual urge. In this case, either dose reduction or stopping the therapy is advised.
Safinamide therapy may cause a condition of uncontrolled involuntary muscle movements (dyskinesia) or worsen existing cases; therefore, the dose should be reduced according to the patient’s reaction to the drug. Sudden withdrawal or rapid dose reduction is not advised as it may lead to increased temperature, altered consciousness, and rigidity of muscles.

Common Side-Effects

SAFINAMIDE : Dizziness, Drowsiness, Lightheadedness

Serious Side-Effects

SAFINAMIDE : Fainting, Loss Of Balance, Mood Swings, Anxiety, Agitation, Hallucinations, Muscle Stiffness

Rare Side-Effects

SAFINAMIDE : Serotonin Syndrome, Diarrhoea, Skin Rash, Nausea, Vomit, Chest Pain, Irregular Heartbeat, Eyes Blurred Vision, Head Headache, Difficulty Breathing

Disease Interactions

SAFINAMIDE can interfere with: Hypotension, Psychosis, Acute Liver Failure, Hypertension, Uveitis

Technical Classification


Storage Conditions

Room Temperature (Between 15 To 25 C)

Available Alternatives

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