ZENGAT P EYE DPS

Overview

ZENGAT P EYE DPS is a Schedule H drug.

ZENGAT P EYE DPS is composed of: GEFITINIB ( ), PREDNISOLONE ( )

Gefitinib is used to treat non-small cell lung cancer. Gefitinib is a cancer medication that interferes with the growth and spread of cancer cells in the body. Gefitinib belongs to a group of drugs called epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors.

Prednisolone is a steroid that prevents the release of substances in the body that cause inflammation. Prednisolone is used to treat many different inflammatory conditions such as arthritis, lupus, psoriasis, ulcerative colitis, allergic disorders, gland (endocrine) disorders, and conditions that affect the skin, eyes, lungs, stomach, nervous system, or blood cells.

Usage

GEFITINIB is generally used to treat: Lung Cancer

PREDNISOLONE is generally used to treat: Arthritis, Lupus, Psoriasis, Ulcerative Colitis

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 6yrs

Q: Can it be taken during pregnancy?
A: Studies indicate Risk – Doctor advice is must

Q: Is it safe to take for someone breastfeeding?
A: Not Safe

Precautions

• Before using this medication, ask your doctor or pharmacist about your medical history, especially of lung disease, severe kidney disease, eye problems, stomach/intestinal ulcers, other stomach/intestinal problems, smoking, cancer that has spread to the bowels.
• Do not take gefitinib if you are allergic to any of its ingredients.
• Before starting gefitinib treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.).   Do not take aspirin, or products containing aspirin unless your doctor specifically permits this.
• Do not receive any kind of immunization or vaccination without your doctor’s approval while taking gefitinib.
• For both men and women: Do not conceive a child (get pregnant) while taking gefitinib. Barrier methods of contraception, such as condoms, are recommended. Discuss with your doctor when you may safely become pregnant or conceive a child after therapy.

Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.
You may need to shake the oral suspension (liquid) well just before you measure a dose. Follow the directions on your medicine label. Keep the disintegrating tablet in its blister pack until you are ready to take the medicine. Open the package using dry hands, and peel back the foil from the tablet blister (do not push the tablet through the foil). Remove the tablet and place it in your mouth. Allow the disintegrating tablet to dissolve in your mouth without chewing. Swallow several times as the tablet dissolves. If desired, you may drink liquid to help swallow the dissolved tablet. Caution should be exercised in patients with the history of increased eye pressure, optic nerve damage, diabetes, during pregnancy and breastfeeding. It may cause blurred vision, do not drive a car or operate machinery while taking this medication.

Symptoms of Overdosage

PREDNISOLONE over-dosage can result in: Difficulty Breathing

Common Side-Effects

GEFITINIB : Eyes Burning Sensation, Chest Pain, Chills, Cough, Difficulty Breathing, Eyes Dry Eyes, Shortness Of Breath
PREDNISOLONE : Depression, Agitation, Anxiety, Eyes Blurred Vision, Decreased Urination, Dizziness, Irregular Heartbeat, Head Headache, Mood Swings, Shortness Of Breath, Difficulty Breathing, Weight Gain, Cough, Throat Soreness, Fever, Chills

Serious Side-Effects

GEFITINIB : Abdomen Pain, Dark Colored (brown) Urine, Decreased Appetite, Fever, Nausea, Vomit
PREDNISOLONE : Fatigue (tiredness), Ankles Swelling, Mood Swings

Rare Side-Effects

GEFITINIB : Bloody Or Red Colored Stools, Eyes Redness, Eyes Eye Irritation, Heartburn, Abdomen Pain, Throat Soreness, Vomit
PREDNISOLONE : Difficulty Breathing, Dizziness, Face Swelling, Body Itching

Food Interactions

Grapefruit may increase serum product levels.

Disease Interactions

PREDNISOLONE can interfere with: Tuberculosis, Latent Tuberculosis, Hypernatremia, Hypokalemia, Seizure, Hypocalcemia, Diverticulitis, Ulcerative Colitis, Bacterial Infection, Fungal Infection, Myocardial Infarction, Ocular Herpes, Premature Aging, Systematic Sclerosis, Strongyloidiasis, Vaccination, Cirrhosis, Depression, Psychosis, Diabetes Mellitus, Impaired Glucose Tolerance, Congestive Heart Disease, Acute Renal Failure, Hypertension, Hyperadrenalism, Hyperlipidemia, Hypothyroidism, Myasthenia Gravis, Myopathy, Glaucoma, Osteoporosis, Purpura, Thrombotic Thrombocytopenic

Technical Classification

GEFITINIB is categorized as: EGFR INHIBITORS / ANTINEOPLASTICS
PREDNISOLONE is categorized as: GLUCOCORTICOIDS / ADRENAL CORTICAL STEROIDS / HORMONES

Available Alternatives

What are the commonly available Substitutes?

GATE P 3MG/10MG EYE DPS	INR 28.35 for 10 ML EYE DROP	PREDNISOLONE 10.0 MG, GEFITINIB 3.0 MG
GATE PD 3MG/10MG EYE DPS	INR 25.9 for 10 ML EYE DROP	PREDNISOLONE 10.0 MG, GEFITINIB 3.0 MG
GATIQUIN P 0.3% W/V/1% W/V EYE DPS	INR 94 for 10 ML EYE DROP	PREDNISOLONE 1.0 %W/V, GEFITINIB 0.3 %W/V
GATSUN P 0.3%/1% DPS	INR 12.84 for 5 ML DROP	PREDNISOLONE 1.0 %W/V, GEFITINIB 0.3 %W/V
PREDZY 3MG/10MG EYE DPS	INR 60 for 5 ML EYE DROP	PREDNISOLONE 10.0 MG, GEFITINIB 3.0 MG
SIOGAT P 0.3%/1% EYE DPS	INR 55.53 for 5 ML EYE DROP	PREDNISOLONE 1.0 %W/V, GEFITINIB 0.3 %W/V
Z PRED 0.3%/1% EYE DPS	INR 51.25 for 5 ML EYE DROP	PREDNISOLONE 1.0 %W/V, GEFITINIB 0.3 %W/V
ZENGAT P EYE DPS	INR 13.1 for 5 ML EYE DROP	GEFITINIB , PREDNISOLONE