KOMBIGLYZE XR 5MG/1000MG

Overview

KOMBIGLYZE XR 5MG/1000MG is a Schedule H drug.

KOMBIGLYZE XR 5MG/1000MG is composed of: METFORMIN (1000 MG), SAXAGLIPTIN (5 MG)

Metformin is an oral diabetes medicine that helps control blood sugar levels.Metformin is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.It works by lowering glucose production in the liver, delaying sugar (glucose) absorption from intestines and increasing the body’s sensitivity to insulin.


Saxagliptin is an oral diabetes medicine that helps control blood sugar levels. It works by regulating the levels of insulin your body produces after eating. Saxagliptin is for people with type 2 diabetes. Saxagliptin is sometimes used in combination with other diabetes medications but is not for treating type 1 diabetes.

Usage

METFORMIN is generally used to treat: Diabetes Type 2
METFORMIN can address symptoms like: Eyes Blurred Vision, Feet Burn, Weight Loss (unintentional)

SAXAGLIPTIN is generally used to treat: Diabetes Type 2

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Ask your doctor

Q: Can it be taken during pregnancy?
A: Considered as Generally Safe – not enough studies to prove risk

How Do I Take It?

KOMBIGLYZE XR 5MG/1000MG is generally taken With Food.

Precautions for KOMBIGLYZE XR 5MG/1000MG and its Constituents


  • You should not use metformin if you have severe kidney disease or diabetic ketoacidosis.
  • You should not use metformin if you are allergic to it.
  • Take metformin exactly as prescribed by your doctor.
  • Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not use this medicine in larger or smaller amounts or for longer than recommended.
  • Take metformin with a meal.
  • Do not crush, chew, or break an extended-release tablet. Swallow the tablet whole.
  • Your blood sugar will need to be checked often, and you may need other blood tests at your doctor’s office.
  • Your doctor may have you take extra vitamin B12 while you are taking this medicine.
  • It may lead to dehydration; drink plenty of water to avoid this problem.
  • Avoid excess dosage.

Caution should be exercised in patients with history of HIV/AIDS, kidney disease, who are taking other medications, any allergy, elderly, children, during pregnancy and breastfeeding. Monitor blood sugar level regularly while taking this medication. Follow diet and exercise program as instructed by your physician.

Symptoms of Overdosage

SAXAGLIPTIN over-dosage can result in: Confusion, Body Excessive Sweating, Rapid Heart Rate (pulse), Slurred Speech, Nausea, Vomit, Rapid Breathing, Fainting, Seizures (uncontrollable Jerking Of Limbs)

Common Side-Effects

METFORMIN : Diarrhoea, Joint Pain, Skin Rash, Anxiety, Depression, Night Terrors, Seizure, Change In Stools, Unusual Taste In Mouth, Abdomen Discomfort, Cough, Fever, Chills, Body Discomfort, Lower Back Pain, Drowsiness, Chest Discomfort, Confusion, Pale Skin, Labored Breathing, Head Headache, Body Excessive Sweating, Slurred Speech, Shortness Of Breath, Fatigue (tiredness), Body Loss Of Movement, Runny Nose, Sneezing
SAXAGLIPTIN : Anxiety, Blood Or Red Colored Urine, Eyes Blurred Vision, Body Pain, Chills, Confusion, Cough, Dizziness, Rapid Heart Rate (pulse), Frequent Urination, Head Headache, Loss Of Voice, Lower Back Pain, Nasal Congestion, Nausea, Runny Nose, Seizures (uncontrollable Jerking Of Limbs), Throat Soreness

Serious Side-Effects

METFORMIN : Indigestion, Heartburn, Breathlessness, Eyes Blurred Vision, Rapid Breathing, Pain With Urination, Belching, Abdomen Bloating Or Fullness, Increased Passing Gas, Loss Of Appetite, Abdomen Upset Stomach
SAXAGLIPTIN : Abdomen Pain, Nausea, Vomit

Rare Side-Effects

METFORMIN : Difficulty Concentrating, Unusual Behavior, Restless (tossing And Turning) Sleep
SAXAGLIPTIN : Skin Rash, Face Swelling, Dizziness, Difficulty Breathing

Disease Interactions

SAXAGLIPTIN can interfere with: Pancreatitis, Acute Renal Failure

Technical Classification

METFORMIN is categorized as: NON-SULFONYLUREAS / ANTIDIABETIC AGENTS / METABOLIC AGENTS
SAXAGLIPTIN is categorized as: DIPEPTIDYL PEPTIDASE 4 INHIBITORS / ANTIDIABETIC AGENTS / METABOLIC AGENTS

Prescription Statistics

Following information is taken from treatment plans advised by our doctors. This is Only for informational purpose and you must seek doctor’s advice if you are not well.

How Frequently is it taken?

Evening57%
Morning23%
Once Daily17%

How long was it prescribed?

7 Days33%
30 Days17%
180 Days17%
90 Days17%
42 Days8%

What is the break-up across patient age-group?

18 to 35yrs13%
35 to 50yrs30%
50 to 60yrs26%
60 to 70yrs26%
70yrs and above4%

What is the gender-breakup across patients?

Females36%

What kind of doctors prescribe this medicine?

Endocrinologist79%
Cardiologist14%
Physician7%

Most common Medicines advised along-side?

LANTUS VIAL13%
CETAPIN-XR 1G TAB13%
DIAMICRON XR 60MG10%
ECOSPRIN TAB 75MG10%

Most common Diagnostic/Lab Tests advised along-side?

FBS (BIOCHEMISTRY)40%
PPBS (BIOCHEMISTRY)37%
LIPID PROFILE (SCREENING)10%
SERUM TSH (ENDOCRINOLOGY)10%
HBA1C (BIOCHEMISTRY)10%

Available Alternatives for KOMBIGLYZE XR 5MG/1000MG

What are the commonly available Substitutes?

KOMBIGLYZE 5MG/1000MG TAB XRINR 357 for 7 TABLET XRMETFORMIN 1000.0 MG, SAXAGLIPTIN 5.0 MG
KOMBIGLYZE XR 5MG/1000MGINR 357 for 7 TABLETSMETFORMIN 1000 MG, SAXAGLIPTIN 5 MG
RIAX M XR 5/1000MG TABINR 357 for 7 TABLETSMETFORMIN 1000 MG, SAXAGLIPTIN 5 MG
RIAX-M XR 5MG/1000MG TABINR 357 for 7 TABLETSMETFORMIN 1000.0 MG, SAXAGLIPTIN 5.0 MG

What are the other drugs with similar Ingredients?

KOMBIGLYZE 5MG/500MG TAB XRINR 329 for 7 TABLET XRMETFORMIN 500.0 MG, SAXAGLIPTIN 5.0 MG
KOMBIGLYZE XR 5MG/500MGINR 329 for 7 TABLETSMETFORMIN 500 MG, SAXAGLIPTIN 5 MG
RIAX-M XR 5MG/500MG TABINR 329 for 7 TABLETSMETFORMIN 500.0 MG, SAXAGLIPTIN 5.0 MG