DENOSUMAB is a Schedule H drug.
Denosumab is a monoclonal antibody. Monoclonal antibodies are made to target and destroy only certain cells in the body. This may help to protect healthy cells from damage.The Prolia brand of denosumab is used to treat osteoporosis in postmenopausal women who have high risk of bone fracture. Denosumab is also used to increase bone mass in women and men with a high risk of bone fracture caused by receiving treatments for certain types of cancer. Denosumab is used to treat bone problems that may occur in people with multiple myeloma or in people with cancer that has spread to the bones. It is also used to treat high blood calcium levels (hypercalcemia) that may occur with cancer. Common side effects of denosumab include red, dry, and itchy skin, back pain, and headache.


DENOSUMAB is generally used to treat: Osteoporosis, Bone Cancer, Multiple Myeloma

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Ask your doctor

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

Q: Is it safe to take for someone breastfeeding?
A: Not Safe

How Do I Take It?

Route of Administration: IV (Intravenous)


  • Denosumab can harm an unborn baby or cause birth defects. Do not use Prolia if you are pregnant. Tell your doctor right away if you become pregnant during treatment.
  • It is not known whether denosumab passes into breast milk or if it could harm a nursing baby. This medicine may also slow the production of breast milk. You should not breast-feed while using denosumab.
  • Before using denosumab, tell your doctor or pharmacist if you are allergic to it or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
  • Before using this medication, tell your doctor or pharmacist your medical history, especially of: low level of calcium in the blood (hypocalcemia), kidney disease.
  • Denosumab is not recommended for use in children except for the treatment of giant cell tumor of the bone (see also Uses section). It may slow down a child’s growth and affect tooth development.

Common Side-Effects

DENOSUMAB : Joint Pain, Paleness, Arms Pain, Jaws Pain, Body Pain, Chest Pain, Chest Discomfort, Chills, Confusion, Cough, Difficulty Breathing, Throat Soreness, Irregular Heartbeat, Fever, Head Headache, Mouth Numbness, Hands Numbness, Lower Back Pain, Weight Gain, Runny Nose, Seizures (uncontrollable Jerking Of Limbs), Sneezing

Serious Side-Effects

DENOSUMAB : Skin Rash, Back Pain, Blood Or Red Colored Urine, Pain With Urination, Frequent Urination, Frequent Urge To Urinate, Legs Pain, Arms Pain

Rare Side-Effects

DENOSUMAB : Bloody Or Red Colored Stools, Constipation, Dark Colored (brown) Urine, Loss Of Appetite, Lower Back Pain, Nausea

Disease Interactions

DENOSUMAB can interfere with: Hypocalcemia

Technical Classification


Storage Conditions

Room Temperature (Between 15 To 25 C)

Available Alternatives

Common Drugs with DENOSUMAB as Ingredient