TOLBUTAMIDE is a Schedule G drug.
Tolbutamide causes the pancreas to produce insulin and increases your body’s response to it.Tolbutamide is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Tolbutamide is not for treating type 1 diabetes.Tolbutamide is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes.


TOLBUTAMIDE is generally used to treat: Diabetes Type 2
TOLBUTAMIDE can address symptoms like: Fatigue (tiredness), Weight Gain, Increased Thirst, Frequent Urination, Eyes Blurred Vision

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Check with your Doctor first

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Ask your doctor

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

How Do I Take It?

TOLBUTAMIDE is generally taken With Food.
Route of Administration: Oral


  • You should not use tolbutamide if you are allergic to tolbutamide, or if have diabetic ketoacidosis.
  • Before taking tolbutamide, tell your doctor if you have taken another oral diabetes medicine or used insulin during the past 2 weeks.Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
  • Your blood sugar will need to be checked often, and you may need other blood tests at your doctor’s office.
  • Your doctor can prescribe a glucagon emergency injection kit to use in case you have severe hypoglycemia and cannot eat or drink.
  • Tolbutamide is only part of a complete treatment program that may also include diet, exercise, weight control, regular blood sugar testing, and special medical care.
  • Do not use two doses at one time.Avoid drinking alcohol. It lowers blood sugar and may interfere with your diabetes treatment.
  • Tolbutamide could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen when you are outdoors.
  • Be careful while driving or operating machinery until you know how Tolbutamide affects you.

Symptoms of Overdosage

TOLBUTAMIDE over-dosage can result in: Confusion, Weakness (generalized), Body Excessive Sweating, Nausea, Slurred Speech, Rapid Heart Rate (pulse), Seizures (uncontrollable Jerking Of Limbs), Anxiety, Pale Skin, Nervousness

Common Side-Effects

TOLBUTAMIDE : Heartburn, Indigestion, Nausea, Abdomen Bloating Or Fullness, Belching, Abdomen Pain, Abdomen Discomfort, Increased Passing Gas, Redness, Head Headache, Dizziness, Weight Gain, Decreased Taste

Serious Side-Effects

TOLBUTAMIDE : Hypoglycemia, Seizure, Body Excessive Sweating, Rapid Heart Rate (pulse), Hands Tingling, Feet Tingling, Eyes Blurred Vision, Easy Bleeding, Eyes Yellow Eyes, Dark Colored (brown) Urine, Body Discoloration

Rare Side-Effects

TOLBUTAMIDE : Diarrhoea, Skin Rash, Itchy Skin, Chills, Fever, Loss Of Appetite, Bloody Or Red Colored Vomit, Bad Breath, Fatigue (tiredness)

Disease Interactions

TOLBUTAMIDE can interfere with: Diabetes Type 1, Diabetic Ketoacidosis, Acute Renal Failure, Acute Liver Failure, Adrenal Insufficiency, Malnutrition, Panhypopituitarism, Peripheral Neuropathy, Anorexia Nervosa, G6PD Deficiency, Hyponatremia, Syndrome Of Inappropriate Antidiuretic Hormone

Technical Classification


Storage Conditions

Room Temperature (Between 15 To 25 C)

Available Alternatives

Common Drugs with TOLBUTAMIDE as Ingredient