GLYBURIDE is a Schedule H drug.
Glyburide is an oral diabetes medicine that helps control blood sugar levels. Glyburide is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Glyburide is not for treating type 1 diabetes. Glyburide comes in tablet form. It is usually taken once daily, with breakfast or the first main meal of the day. Sometimes a second daily dose is required. Glyburide should be used with diet and exercise, and sometimes other medications, to manage blood sugar levels in type 2 diabetes.


GLYBURIDE is generally used to treat: Diabetes Mellitus, Diabetes Type 2

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Check with your Doctor first

Q: Is it safe for children?
A: Ask your doctor

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

How Do I Take It?

GLYBURIDE is generally taken With Food.
Route of Administration: Oral


  • Before taking glyburide, tell your doctor or pharmacist if you are allergic to it or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
  • Before using this medication, tell your doctor or pharmacist your medical history, especially of liver disease, kidney disease, thyroid disease, certain hormonal conditions (adrenal/pituitary insufficiency, syndrome of inappropriate antidiuretic hormone-SIADH), electrolyte imbalance (hyponatremia), a certain nervous system problem (autonomic neuropathy).
  • You may experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely.
  • Limit alcohol while taking this medication because it can increase the risk of developing low blood sugar. Rarely, alcohol can interact with glyburide and cause a serious reaction (disulfiram-like reaction) with symptoms such as facial flushing, nausea, vomiting, dizziness, or stomach pain.
  • This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors.
  • Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
  • Older adults may be more sensitive to the side effects of this drug, especially low blood sugar.
  • During pregnancy, this medication should be used only when clearly needed. Pregnancy may cause or worsen diabetes. Discuss a plan with your doctor for managing your blood sugar while pregnant. Your doctor may substitute insulin for this drug during pregnancy. If glyburide is used, it may be switched to insulin at least 2 weeks before the expected delivery date because of glyburide’s risk of causing low blood sugar in your newborn.
  • It is unknown if this medication passes into breast milk. However, similar drugs pass into breast milk. Consult your doctor before breast-feeding.

Symptoms of Overdosage

GLYBURIDE over-dosage can result in: Rapid Heart Rate (pulse), Body Excessive Sweating

Common Side-Effects

GLYBURIDE : Hives, Itchy Skin, Skin Rash, Difficulty Swallowing, Dizziness, Rapid Heart Rate (pulse), Shortness Of Breath, Fatigue (tiredness), Weakness (generalized), Wheezing

Rare Side-Effects

GLYBURIDE : Diarrhoea, Abdomen Pain, Chills, Change In Stools, Dark Colored (brown) Urine, Loose Motion, Fever, Head Headache, Loss Of Appetite, Nausea, Vomit, Bloody Or Red Colored Vomit

Disease Interactions

GLYBURIDE can interfere with: Hypoglycemia, G6pd Deficiency, Hyponatremia, Acute Liver Failure, Acute Kidney Failure

Technical Classification


Storage Conditions

Room Temperature (Between 15 To 25 C)

Available Alternatives

Common Drugs with GLYBURIDE as Ingredient