COSYNTROPIN is a Schedule H drug.
Cosyntropin is a man-made form of a hormone called adrenocorticotropic hormone (ACTH). ACTH is a hormone that is normally produced by the pituitary gland in the brain. ACTH stimulates the adrenal glands to release the hormones cortisol and adrenaline. These hormones help your body respond to stress and also support many systems of the body including circulation, metabolism, immunity, and the nervous system.Cosyntropin is used as part of a medical test called an ACTH stimulation test. This test can help your doctor diagnose adrenal gland disorders such as Addison’s disease, Cushing syndrome, or hypopituitarism (failure of the pituitary gland to produce hormones correctly).

Frequently Asked Questions

Q: Is it safe on my liver?
A: Check with your Doctor first

Q: Is it safe on my kidney?
A: Check with your Doctor first

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 1month

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

Q: Is it safe to take for someone breastfeeding?
A: Check with your Doctor first

How Do I Take It?

Route of Administration: IV (Intravenous)


  • Before you receive cosyntropin, tell your doctor about all your medical conditions or allergies, and all the medicines you are using.
  • You should not be treated with cosyntropin if you are allergic to it.Cosyntropin is injected into a muscle, or into a vein through an IV. A healthcare provider will give you this injection.
  • Before you receive cosyntropin, your blood will be drawn to measure your "baseline" level of certain hormones.
  • Your blood will be drawn again 30 to 60 minutes after cosyntropin was injected, to measure your hormone levels and compare them to the baseline levels.
  • This will help your doctor determine if your pituitary and adrenal functions are normal.Follow your doctor’s instructions about any restrictions on food, beverages, or activity.

Symptoms of Overdosage

COSYNTROPIN over-dosage can result in: Difficulty Breathing

Serious Side-Effects

COSYNTROPIN : Hives, Skin Rash, Itchy Skin, Dizziness, Tachycardia, Difficulty Swallowing, Difficulty Breathing, Mouth Swelling, Face Swelling, Irregular Heartbeat, Legs Swelling, Arms Swelling

Disease Interactions

COSYNTROPIN can interfere with: Tuberculosis, Hypocalcemia, Adrenal Insufficiency, Hypernatremia, Hypokalemia, Seizure, Congestive Heart Disease, Hypertension, Acute Renal Failure, Diverticulitis, Ulcerative Colitis, Bacterial Infection, Fungal Infection, Ocular Herpes, Osteoporosis, Peptic Ulcer, Vaccination, Cirrhosis, Psychosis, Depression, Diabetes Mellitus, Impaired Glucose Tolerance, Glaucoma, Hypothyroidism, Myasthenia Gravis, Myopathy

Technical Classification


Storage Conditions

Room Temperature (Between 15 To 25 C)

Available Alternatives

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