Methadone is used as a pain reliever and as part of drug addiction detoxification and maintenance programs. Methadone is an opioid medication. An opioid is sometimes called a narcotic. Methadone reduces withdrawal symptoms in people addicted to heroin or other narcotic drugs without causing the "high" associated with the drug addiction.


METHADONE HYDROCHLORIDE is generally used to treat: Drug Abuse, Addiction

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Ask your doctor

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

Q: Is it safe to take for someone breastfeeding?
A: Not Safe

How Do I Take It?

Route of Administration: Oral,


  • Before taking methadone, tell your doctor or pharmacist if you are allergic to it or if you have any other allergies.
  • Methadone may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious fast/irregular heartbeat and other symptoms that need medical attention right away.
  • Some products may contain sugar. Caution is advised if you have diabetes. Ask your doctor or pharmacist about using this product safely.
  • Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
  • During pregnancy, this medication should be used only when clearly needed. It may harm an unborn baby. Discuss the risks and benefits with your doctor.
  • This drug passes into breast milk and may have undesirable effects on a nursing infant. Tell the doctor right away if your baby develops unusual sleepiness, difficulty feeding, or trouble breathing.
  • It may cause drowsiness, dizziness, blurred vision, or lightheadedness, do not drive a car or operate machinery and get up slowly from bed while taking this medication.
  • Avoid alcohol consumption.
  • Monitor patient’s condition during treatment initiation, during conversion from one opioid to another, and during dose titration.

Symptoms of Overdosage

METHADONE HYDROCHLORIDE over-dosage can result in: Slow Heart Rate (pulse), Difficulty Breathing, Rapid Heart Rate (pulse)

Common Side-Effects

METHADONE HYDROCHLORIDE : Constipation, Weakness (generalized), Head Headache, Nausea, Vomit, Weight Gain, Loss Of Appetite, Abdomen Pain, Tongue Soreness, Dry Mouth, Body Excessive Sweating, Mood Swings, Difficulty Urinating, Eyes Change In Vision, Unusual Behavior, Irregular Menstrual Periods, Missed Or Late Menstrual Period

Serious Side-Effects

METHADONE HYDROCHLORIDE : Hives, Skin Rash, Itchy Skin, Seizures (uncontrollable Jerking Of Limbs), Pounding Heart (pulse), Restless Or Irritability, Difficulty Breathing, Difficulty Swallowing, Drowsiness, Fainting, Hallucinations

Food Interactions

Grapefruit juice can increase the blood levels and effects of methadone. If you regularly consume grapefruits or grapefruit juice, you should be monitored for side effects and/or changes in methadone levels. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. Orange juice is not expected to interact.

Disease Interactions

METHADONE HYDROCHLORIDE can interfere with: Gastritis, Constipation, Diarrhoea, Enterocolitis, Gastroenteritis, Acute Liver Failure, Acute Renal Failure, Alcoholism, Drug Abuse, Drug Dependence, Hypotension, Shock, Asphyxia Neonatorum, Adrenal Insufficiency, Hypothyroidism, Panhypopituitarism, Seizure, Urinary Retention, Heart Arrhythmias

Technical Classification


Storage Conditions

Room Temperature (Between 15 To 25 C)

Available Alternatives

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