- 1 Overview
- 2 Usage
- 3 Frequently Asked Questions
- 4 How Do I Take It?
- 5 Precautions
- 6 Symptoms of Overdosage
- 7 Common Side-Effects
- 8 Serious Side-Effects
- 9 Rare Side-Effects
- 10 Food Interactions
- 11 Disease Interactions
- 12 Technical Classification
- 13 Storage Conditions
- 14 Available Alternatives
- 15 Share this:
- 16 Like this:
- 17 Related Articles
OverviewCABOZANTINIB is a Schedule H drug.
This medication is used to treat certain types of cancer (including kidney, thyroid cancer). Cabozantinib belongs to a class of drugs known as tyrosine kinase inhibitors. It works by slowing or stopping the growth of cancer cells. Cabozantinib is also available as a tablet (Cabometyx) to treat advanced renal cell carcinoma.
UsageCABOZANTINIB is generally used to treat: Kidney Cancer, Thyroid Cancer, Renal Cell Carcinoma
Frequently Asked QuestionsQ: Is it safe on my liver?
A: Not Safe
Q: Can I take it with alcohol?
A: Not Safe
Q: Is it safe for children?
A: Ask your doctor
Q: Can it be taken during pregnancy?
A: Studies indicate Risk – Doctor advice is must
How Do I Take It?CABOZANTINIB is generally taken Before Food.
Route of Administration: Oral
- Before taking Cabozantinib know yourself If you have any other allergies, this product may contain inactive ingredients, which can cause allergic reactions or other problems.
- Before using this medication, tell your doctor or pharmacist your medical history, especially of liver disease, recent bleeding (including recently coughing up blood), high blood pressure.
- Cabozantinib can make you more likely to get infections or may worsen any current infections. Do not have immunizations/vaccinations without the consent of your doctor. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose).
- To lower the chance of getting cut, bruised, or injured, use caution with sharp objects like razors and nail cutters, and avoid activities such as contact sports.
- Pain or sores in the mouth and throat may occur. Brush your teeth carefully/gently, avoid using mouthwash that contains alcohol, and rinse your mouth frequently with cool water. It may also be best to eat soft, moist foods.
- Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while you are using cabozantinib. Cabozantinib may harm an unborn baby.
- Patient may develop severe bleeding episodes (serious effects) that can lead to death. If it is so consult with your healthcare provider.
- Tell your healthcare provider right away, if you experience frequent loose, watery bowel movements. Your healthcare provider may prescribe medicine to treat your diarrhea or may stop your treatment for a while.
Symptoms of OverdosageCABOZANTINIB over-dosage can result in: Blackouts (memory Time Loss), Confusion, Weight Loss (unintentional)
Common Side-EffectsCABOZANTINIB : Indigestion, Paralysis, Hypotension, Thromboembolism, Atrial Fibrillation, Cholelithiasis, Hemorrhoids, Pancreatitis, Hypothyroidism, Folliculitis, Acne, Osteonecrosis, Dysuria, Hematuria (Blood In Urine), Gums Bleeding, Black (tar) Colored Stools, Cough, Heartburn, Vagina Bleeding, Nausea, Mouth Pain, Mouth Numbness, Mouth Swelling, Dark Colored (brown) Urine, Abdomen Pain, Difficulty Breathing, Vomit
Serious Side-EffectsCABOZANTINIB : Skin Cancer, Skin Rash, Allergic Skin Disease, Hyperbilirubinemia, Hypertension, Stomatitis, Dysphagia, Dysphasia, Neutropenia, Thrombocytopenia, Alopecia, Erythema, Hypocalcemia, Hypokalemia, Hyponatremia, Abscess, Tinnitus, Peripheral Neuropathy, Eyes Blurred Vision, Difficulty Breathing, Difficulty Swallowing, Dizziness, Head Headache, Nervousness, Chest Pain, Legs Pain, Slow Heart Rate (pulse), Rapid Heart Rate (pulse), Slurred Speech, Loss Of Coordination, Arms Numbness, Legs Numbness, Eyes Change In Vision
Rare Side-EffectsCABOZANTINIB : Night Blindness, Seizure, Angina Pectoris, Tachycardia, Hepatic Encephalopathy, Esophagitis, Amenorrhoea, Rhabdomyolysis, Conjunctivitis, Delirium, Confusion, Eyes Double Vision (with One Eye Covered), Eyes Visual Halos Around Lights
Food InteractionsAvoid grapefruit juice. Combination may increase levels of cabozantinib. Also avoid all other strong CYP3A4 inhibitors.
Disease InteractionsCABOZANTINIB can interfere with: Hemorrhage, Thromboembolism, Hypertension
Technical ClassificationCABOZANTINIB is categorized as:
- MULTIKINASE INHIBITORS / ANTINEOPLASTICS
- VEGF/VEGFR INHIBITORS / ANTINEOPLASTICS
Storage ConditionsRoom Temperature (Between 15 To 25 C)
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