SIROLIMUS

Overview

SIROLIMUS is a Schedule H drug.
Sirolimus is an immunosuppressant. It works by suppressing your body’s immune response following transplant of an organ (eg. liver, kidney, heart). This helps your body to accept the new organ as if it were your own. Sirolimus is used to prevent prevention of kidney transplant rejection. Sirolimus is also given without other medicines to treat a rare lung disorder called lymphangioleiomyomatosis (Lim-FAN-gee-oh-LYE-oh-MYE-oh-ma-TOE-sis). This disorder happens mostly in women and causes lung tumors that are not cancerous but can affect breathing.

Usage

SIROLIMUS is generally used to treat: Lymphangioleiomyomatosis

Frequently Asked Questions

Q: Is it safe on my liver?
A: Check with your Doctor first

Q: Is it safe on my kidney?
A: Check with your Doctor first

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 12yrs

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

How Do I Take It?

SIROLIMUS is generally taken With Food.
Route of Administration: Oral

Precautions

Caution should be exercised in patients with history of liver, kidney problems, high cholesterol, low blood platelet levels, diabetes, lung or breathing problems, any allergy, infections, who are taking other medications especially for HIV or Hepatitis C , during pregnancy and breastfeeding. Avoid contact with people who have infections. Patient may develop with increased risk of progressive multifocal leukoencephalopathy (PML), severe kidney problems, certain types of cancer; if it is so consult with your doctor. Avoid live vaccination while taking this medication. It may affect blood sugar level; monitor sugar level regularly while taking this medication.


Symptoms of Overdosage

SIROLIMUS over-dosage can result in: Difficulty Breathing

Common Side-Effects

SIROLIMUS : Loose Motion, Arms Joint Pain, Difficulty Sleeping

Serious Side-Effects

SIROLIMUS : Abdomen Stomach Cramps, Back Pain, Black (tar) Colored Stools, Confusion, Cough, Dark Colored (brown) Urine, Dizziness, Drowsiness, Dry Mouth, Eyes Pain, Irregular Heartbeat, Fever, Nasal Congestion, Nausea, Vomit, Pale Skin, Runny Nose, Constipation, Head Headache, Throat Soreness, Ankles Swelling, Abdomen Pain, Chest Pain, Shortness Of Breath

Rare Side-Effects

SIROLIMUS : Face Swelling, Dizziness, Difficulty Breathing

Disease Interactions

SIROLIMUS can interfere with: Bacterial Infection, Fungal Infection, Angioedema, Hyperlipidemia, Acute Liver Failure, Acute Renal Failure

Technical Classification

SIROLIMUS is categorized as:
  • MTOR INHIBITORS / ANTINEOPLASTICS
  • SELECTIVE IMMUNOSUPPRESSANTS / IMMUNOSUPPRESSIVE AGENTS / IMMUNOLOGIC AGENTS

Storage Conditions

Room Temperature (Between 15 To 25 C)

Available Alternatives

Common Drugs with SIROLIMUS as Ingredient

EMTOR 1MG TABSIROLIMUS 1.0 MG
GENXTOR 25MG INJSIROLIMUS 25.0 MG
LIMUS 1MG TABSIROLIMUS 1.0 MG
RAPACAN 1MG CAPSIROLIMUS 1.0 MG
RAPACAN 2MG CAPSIROLIMUS 2.0 MG
RAPAMUNE 1MG TABSIROLIMUS 1.0 MG
RAPAREN 1MG INJSIROLIMUS 1.0 MG
RAPAREN 1MG TABSIROLIMUS 1.0 MG
ROCAS 1MG TABSIROLIMUS 1.0 MG
SIROMUS 1MG TABSIROLIMUS 1.0 MG
SIROPAN 1MG TABSIROLIMUS 1.0 MG
SIROVA 1MG TABSIROLIMUS 1.0 MG