METHOTREXATE

Overview

METHOTREXATE is a Schedule H drug.
Methotrexate decreases the activity of the immune system and slows cancer cell growth. Reserved for conditions that cannot be treated with other medications.Methotrexate is used in the treatment of rheumatoid arthritis and psoriasis.Methotrexate is an immunosuppressant. In rheumatoid arthritis, it works by decreasing the activity of body’s immune system. This decreases swelling, reduces pain and stiffness, and improves function. In psoriasis, it works by slowing down the rapid growth of skin cells.

Usage

METHOTREXATE is generally used to treat: Rheumatoid Arthritis, Psoriasis, Head Cancer, Neck Cancer, Breast Cancer, Skin Cancer, Lung Cancer, Arthritis, Juvenile
METHOTREXATE can address symptoms like: Joint Pain, Back Pain, Fatigue (tiredness), Redness, Spinning Sensation, Hands Swelling, Dry Mouth, Pale Skin

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 3yrs

Q: Can it be taken during pregnancy?
A: Dangerous – Studies indicate Human-Fetal Risk

How Do I Take It?

Route of Administration: IM (Intra-Mascular), ,

Precautions

  • Methotrexate is usually not taken every day.
  • You must use the correct dose for your condition.
  • Do not use methotrexate to treat psoriasis or rheumatoid arthritis if you have low blood cell counts, a bone marrow disorder, liver disease (especially if caused by alcoholism), or if you are pregnant or breast-feeding.
  • You should not use methotrexate if you are allergic to it.
  • Do not give this medicine to a child without the advice of a doctor.Take methotrexate exactly as it was prescribed for you Follow all directions on your prescription label and read all medication guides or instruction sheets.
  • Methotrexate is sometimes taken once or twice per week and not every day.
  • You must use the correct dose. Some people have died after taking methotrexate every day by accident.
  • Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).
  • Your blood will need to be tested often, If you need to be sedated for dental work, tell your dentist you currently use this medicine.
  • Do not receive a "live" vaccine while using methotrexate, or you could develop a serious infection.
  • This medicine can pass into body fluids (urine, feces, vomit). Caregivers should wear rubber gloves while cleaning up a patient’s body fluids, handling contaminated trash or laundry or changing diapers.
  • Wash hands before and after removing gloves.
  • Wash soiled clothing and linens separately from other laundry.Avoid exposure to sunlight or artificial UV rays, especially if you are being treated for psoriasis. Methotrexate can make your skin more sensitive to sunlight and your psoriasis may worsen.
  • Always take folic acid as advised by your doctor. This will help lessen the side effects of Methotrexate.

Common Side-Effects

METHOTREXATE : Acne, Skin Rash, Itchy Skin, Diarrhoea, Dyspepsia, Stomatitis, Fever, Chills, Fatigue (tiredness), Mouth Soreness, Nausea, Abdomen Upset Stomach, Dizziness, Abdomen Pain, Back Pain, Eyes Blurred Vision, Confusion, Cough, Dark Colored (brown) Urine, Drowsiness, Head Headache, Pain With Urination, Lower Back Pain, Shortness Of Breath, Eyes Yellow Eyes, Easy Bruising, Vomit, Pale Skin, Loss Of Appetite

Serious Side-Effects

METHOTREXATE : Anemia, Acute Liver Failure, Acute Kidney Failure, Black (tar) Colored Stools, Blood Or Red Colored Urine, Bloody Or Red Colored Stools, Bloody Or Red Colored Vomit, Joint Pain, Feet Swelling, Hair Loss, Decreased Urination, Chest Discomfort, Weight Loss (unintentional), Face Swelling, Swollen Lips, Eyes Swelling, Swollen Tongue, Arms Swelling

Food Interactions

 If you are receiving methotrexate for arthritis, you may want to limit your intake of caffeine-containing foods and products.

Disease Interactions

METHOTREXATE can interfere with: Fungal Infection, Protozoal Infection, Viral Inection, Bacterial Infection, Acute Liver Failure, Alcoholism, Bone Marrow Suppression, Anemia, Acute Renal Failure, Pleural Effusion, Peptic Ulcer, Diarrhoea, Inflammatory Bowel Disease

Technical Classification

METHOTREXATE is categorized as:
  • ANTIMETABOLITES / ANTINEOPLASTICS
  • ANTIPSORIATICS / MISCELLANEOUS AGENTS
  • ANTIRHEUMATICS / MISCELLANEOUS AGENTS
  • OTHER IMMUNOSUPPRESSANTS / IMMUNOSUPPRESSIVE AGENTS / IMMUNOLOGIC AGENTS

Storage Conditions

Room Temperature (Between 15 To 25 C)

Available Alternatives

Common Drugs with METHOTREXATE as Ingredient

FOLITRAX 10 MGTABMETHOTREXATE 10 MG
FOLITRAX 10MG TABMETHOTREXATE 10.0 MG
FOLITRAX 15MG INJMETHOTREXATE 15.0 MG
FOLITRAX 15MG TABMETHOTREXATE 15 MG
FOLITRAX 2.5MG TABMETHOTREXATE 2.5 MG
FOLITRAX 20MG INJMETHOTREXATE 20.0 MG
FOLITRAX 20MG TABMETHOTREXATE 20 MG
FOLITRAX 25MG INJMETHOTREXATE 25.0 MG
FOLITRAX 25MG TABMETHOTREXATE 25.0 MG
FOLITRAX 50MG INJMETHOTREXATE 50.0 MG
FOLITRAX 5MG TABMETHOTREXATE 5 MG
FOLITRAX 7.5MG INJMETHOTREXATE 7.5 MG
FOLITRAX 7.5MG TABMETHOTREXATE 7.5 MG
FOLITRAX AMP 15MG X1MLMETHOTREXATE 15 MG
FOLITRAX AMP 25MG X 1MLMETHOTREXATE 25 MG
FOLITRAX AMP 7.5MG X 1MLMETHOTREXATE 7.5 MG
FOLITRAX INJMETHOTREXATE 20 MG
HITREX 15MG INJMETHOTREXATE 15.0 MG
HITREX 50MG INJMETHOTREXATE 50.0 MG
IMUTREX 10MG TABMETHOTREXATE 10.0 MG
IMUTREX 15MG INJMETHOTREXATE 15.0 MG
IMUTREX 2.5MG TABMETHOTREXATE 2.5 MG
IMUTREX TAB 7.5MGMETHOTREXATE 7.5 MG
MEDITREX 10MG TABMETHOTREXATE 10.0 MG
MEDITREX 15MG TABMETHOTREXATE 15.0 MG
MEDITREX 5MG TABMETHOTREXATE 5.0 MG
MEDITREX 7.5MG TABMETHOTREXATE 7.5 MG
MEREX 1000MG INJMETHOTREXATE 1000.0 MG
MEREX 500MG INJMETHOTREXATE 500.0 MG
METH 2.5MG TABMETHOTREXATE 2.5 MG
METHOCEL 1000MG INJMETHOTREXATE 1000.0 MG
METHOCEL 15MG INJMETHOTREXATE 15.0 MG
METHOCEL 2.5MG TABMETHOTREXATE 2.5 MG
METHOCEL 500MG INJMETHOTREXATE 500.0 MG
METHOCEL 50MG INJMETHOTREXATE 50.0 MG
METHOCIP 50MG INJMETHOTREXATE 50.0 MG
METHOCIP 50MG TABMETHOTREXATE 50.0 MG
METHOFAST 15MG INJMETHOTREXATE 15.0 MG
METHOFAST 50MG INJMETHOTREXATE 50.0 MG
METHOREX 2.5MG TABMETHOTREXATE 2.5 MG
MEXATE 10MG TABMETHOTREXATE 10 MG
MEXATE 15MG TABMETHOTREXATE 15 MG
MEXATE 2.5MG TABMETHOTREXATE 2.5 MG
MEXATE 5MG TABMETHOTREXATE 5 MG
MEXATE 7.5MG TABMETHOTREXATE 7.5 MG
MEXATE COMBIPACK 25MG INJMETHOTREXATE 25.0 MG
MEXT 10MG TABMETHOTREXATE 10 MG
MEXT 15MG TABMETHOTREXATE 15.0 MG
MEXT 2.5MG TABMETHOTREXATE 2.5 MG
MEXT 5MG TABMETHOTREXATE 5.0 MG
MEXT 7.5MG TABMETHOTREXATE 7.5 MG
MEXT F 7.5MG/1MG TABMETHOTREXATE 7.5 MG, FOLIC ACID 1.0 MG
NEOTREXATE 2.5MG TABMETHOTREXATE 2.5 MG
NEOTREXATE INJMETHOTREXATE 50.0 MG
NEOTREXATE TABMETHOTREXATE 2.5 MG
ONCOTREX 10MG TABMETHOTREXATE 10 MG
ONCOTREX 2.5MG TABMETHOTREXATE 2.5 MG
ONCOTREX 50MG INJMETHOTREXATE 50.0 MG
ONCOTREX 5MG TABMETHOTREXATE 5.0 MG
ONCOTREX 7.5MG TABMETHOTREXATE 7.5 MG
PSORIAX 5MG TABMETHOTREXATE 5.0 MG
REMTREX 15MG INJMETHOTREXATE 15.0 MG
REMTREX 2.5MG TABMETHOTREXATE 2.5 MG
REMTREX 50MG INJMETHOTREXATE 50.0 MG
REMTREX INJMETHOTREXATE
RHUTRAX 15MG TABMETHOTREXATE 15.0 MG
RHUTRAX 7.5MG TABMETHOTREXATE 7.5 MG
RHUTREX 10MG TABMETHOTREXATE 10.0 MG
TREX 2.5MG TABMETHOTREXATE 2.5 MG
TREXOPAR 15MG INJMETHOTREXATE 15.0 MG
TREXOPAR 50MG INJMETHOTREXATE 50.0 MG
TRUXOFOL 7.5MG/1MG TABMETHOTREXATE 7.5 MG, FOLIC ACID 1.0 MG
UNITREXATE 15MG INJMETHOTREXATE 15.0 MG
UNITREXATE 50MG INJMETHOTREXATE 50.0 MG
UNITREXATE INJMETHOTREXATE 5 MG/ML
VIBZI 5MG TABMETHOTREXATE 5.0 MG
ZEXATE 5MG INJMETHOTREXATE 5 MG